• WNT signaling is well recognized for its role

  2018-10-24

  

  WNT signaling is well recognized for its role in regulating stem and progenitor ll-37 in diverse systems (Nusse et al., 2008). Elevated levels of β-catenin, indicative of aberrant WNT signaling, are reported in more than 50% of human breast carcinomas, correlate with poor prognosis, and are prefere

• Pirfenidone We next aimed to characterize changes in

  2018-10-24

  

  We next aimed to characterize changes in huSCs during ex vivo culture, which, in mice, results in a marked reduction in the capacity for tissue regeneration and self-renewal upon subsequent transplantation (Gilbert et al., 2010; Montarras et al., 2005). For this analysis, we used a basal culture med

• Recently several studies have suggested that peripheral

  2018-10-24

  

  Recently, several studies have suggested that peripheral blood mononuclear bupropion hydrochloride (PBMCs) are a promising resource for generating iPSCs because most of these cells do not undergo TCR rearrangement (Loh et al., 2010; Mack et al., 2011; Seki et al., 2010). However, PBMCs are composed

• br Results br Discussion We

  2018-10-24

  

  Results Discussion We report the development of a method to generate and proliferate iCx26GJCs from mouse iPSCs for use as a disease model and in inner-ear cell therapies targeting GJB2-related hearing loss, the most frequent type of hereditary deafness worldwide. Our induction method until da

• In this article we searched for genes that

  2018-10-24

  

  In this article, we searched for genes that are induced by KLF4 in a dose-dependent manner and identified Tcl1 as its direct target. KLF4 induces Tcl1 transcription during reprogramming via direct binding to its enhancer and promoter regions, concurrently changing repressive histone marks into activ

• Using Eqs and the expression for the matrix element of

  2018-10-24

  

  Using Eqs. (10) and (11), the expression for the matrix lxr agonist of the dipole operator can be represented in the form where Here is the reducible self-energy part of Green\'s function; the integration is once again performed over the whole set of HF states. This, using Eq. (12), the ampl

• Introduction Recent studies on the effect of spatial curvatu

  2018-10-24

  

  Introduction Recent studies on the effect of spatial curvature of the common carotid artery on blood flow [1–3] suggest that Ibrutinib flows with axisymmetric velocity distributions in the arterial cross-sections virtually never occur. As proved by the results of the computations performed for spat

• We also examined ovarian cancer mortality in the

  2018-10-23

  

  We also examined ovarian cancer mortality; in the high exposure period, the RR reduced to 0.62 (95% CI 0.38–1.02; 2-tailed p=0.06). Since with ovarian cancer we had a clear a priori hypothesis that mortality might be reduced based on our breast cancer findings, we also calculated a 1-tailed test of

• Conflicts of interest br Introduction The goal of islet tran

  2018-10-23

  

  Conflicts of interest Introduction The goal of islet transplantation is to use the donor β-cells to restore the insulin production and glycemic regulation in patients with type 1 diabetes to avoid serious complications (Barton et al., 2012; Goland and Egli, 2014). For long-term graft survival, n

• Research was supported by Leukaemia

  2018-10-23

  

  Research was supported by Leukaemia Lymphoma Research UK (LLR Grant10016 to MFK, LLR Gordon Piller Studentship award Grant11043 to MFK, AK, DP), by an MRC-Imperial Confidence-in-Concept (ICiC) grant to MFK, and by the NIHR Biomedical Research Centre at Imperial College NHS Trust, London. Results

• Interestingly in their simulation model Lodding and colleagu

  2018-10-23

  

  Interestingly, in their simulation model, Lodding and colleagues were able to predict their real rate of recipients with a high CMV viral load (1.4%, arbitrarily set at >18,200IU/mL) with the assumption of their lower doubling time of 4.3days. Using a shorter doubling time of 1.3days, the proportion

• br Introduction The Middle East respiratory syndrome coronav

  2018-10-23

  

  Introduction The Middle East respiratory syndrome coronavirus (MERS-CoV) is the only lineage C betacoronavirus known to infect humans (Annan et al., 2013; Anthony et al., 2013; van Boheemen et al., 2012). Similarly to severe acute respiratory syndrome coronavirus (SARS-CoV), MERS-CoV infection ca

• br Introduction Tuberculous TB pericarditis accounts for of

  2018-10-23

  

  Introduction Tuberculous (TB) pericarditis accounts for 50–70% of pericardial disease in Africa (Mayosi et al., 2005, 2006, 2008). Mortality rates range between 17 and 60% (Mayosi et al., 2008; Pusch et al., 2014; Shaw et al., 2010). The Investigation of the Management of Pericarditis (IMPI) regi

• However it is assumed to take into consideration

  2018-10-23

  

  However, it transferases is assumed to take into consideration the high costs of the of CD31+/annexin V+ EMPs to CD14+CD309+ cell ratio versus traditional circulating biomarkers\' assessment using ELISA tests. Probably, this might be a limitation for a wide implementation of the assay in the routin

• The impact of WL on ASCs is unknown

  2018-10-23

  

  The impact of WL on ASCs is unknown. By comparing ASCs from abdominal sWAT of normal weight (NWD), obese (OD) and long-term weight-losing formerly obese donors (WLDs) we showed that long-term WL amongst others reduced the adipogenic activity in these AP20187 Supplier (Mitterberger et al., 2014b). T

16376 records 1088/1092 page Previous Next First page 上5页 10861087108810891090 下5页 Last page