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Of note is that a minimal improvement
2018-10-23
Of note is that a minimal improvement, both in cognitive and neuroanatomical measures, was demonstrated in the OSA patients randomized to BSC over one month (Table 2, Supplementary Table S3). Similar improvement in patients with OSA has been previously associated with the improved sleep quality and
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Gut Microbiome and Inflammatory Bowel
2018-10-23
Gut Microbiome and Inflammatory Bowel Disease Modulation of Gut Microbiota in Obesity and Cardiometabolic Disorders Changes in gut microbiota are associated with metabolic disorders such as obesity, type 2 diabetes and cardiovascular risk factors. Patrice D. Cani (Brussels, Belgium), Willem M. d
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Previous work showed that lncRNAs
2018-10-23
Previous work showed that lncRNAs show higher tissue specificity compared to mRNAs (). The work of Ching et al. supported this notion, and extended it by showing a reduction of specificity after malignant transformation, which is consistent with the de-differentiation status of cancers widely observ
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Of note it is not known whether the
2018-10-23
Of note, it is not known whether the findings observed in the HOD model will translate to murine RBCs expressing other antigens, or to humans. Human studies investigating the role of RBC storage duration on alloimmunization and other adverse effects have reported varied outcomes (Dinardo et al., 201
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Despite its description over years ago by German
2018-10-23
Despite its description over 100years ago by German psychiatrist Alois Alzheimer, there has been little effective translation of insights on Alzheimer\'s disease (AD) pathobiology into effective treatments. As of 2015, roughly 50 million people globally — most over the age of 65years — have dementia
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Linnman et al reanalyzed the NK receptor data in
2018-10-23
Linnman et al. (2012) reanalyzed the NK1 receptor data in cWAD patients and healthy controls from an already published study (Linnman et al., 2010). This was done to validate if the NK1 receptor availability was altered in the posterior parietal occipital region as previously reported by others (Lin
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motilin receptor br Contributors br Declaration of Interests
2018-10-23
Contributors Declaration of Interests Acknowledgements The Etiology, Risk Factors and Interactions of Enteric Infections and Malnutrition and the Consequences for Child Health and Development Project (MAL-ED) is carried out as a collaborative project supported by the Bill & Melinda Gates Fo
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dna ligase A major question which arises from the aforementi
2018-10-23
A major question which arises from the aforementioned work is if activation of a DDR within telomere repeats indicates physical DNA double stranded breaks or is merely changes in chromatin without an associated lesion. Recently, a new method has been developed which allows the accurate detection of
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The most surprising data for
2018-10-23
The most surprising data for us was the behavior of α-synuclein protein; it accumulated in the dopaminergic neurons of the substantia nigra in response to MPTP treatment, and it failed to accumulate during the treatment with KUSs and esculetin (Fig. 9). Related with this, very recently it has been r
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LC MS configuration Nanoscale LC separation of the tryptic p
2018-10-23
LC-MS configuration Nanoscale LC separation of the tryptic peptides was performed with a NanoAcquity system (Waters Corporation). Samples were loaded on to a Symmetry C18 5μm, 2cm×180μm trap column (Waters) at a flow rate of 5μl/min prior to separation on a Bridged Ethyl Hybrid C18 1.7μm, 25cm×75μm
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br Data format The benchmark
2018-10-23
Data format The benchmark data are distributed in comma-separated value format (csv). Some basic description for each data set is also distributed in automated report files given in PDF format. The delimiter between fields in the csv files is the “,” symbol. The approximate size of the data set f
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br Experiment hydrogen peroxide exposure with SH
2018-10-23
Experiment 4: hydrogen peroxide exposure with SH-SY5Y neurons SH-SY5Y neuronal LJI308 were cultured without experimental perturbation for a minimum of 5 passages. Cells were then changed to media containing either 200nM or 0nM H2O2 for 2h at least 24h after the previous media change. Cells were
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We have reported that retinoids both
2018-10-23
We have reported that retinoids, both RAs and retinoic Phenyl sulfate receptor (RAR)/retinoid X receptor (RXR) analogs, are capable of enhancing macrophage cholesterol efflux, and these events involve activation of the LXR pathway [1,2]. Specifically, retinoid mediated macrophage cholesterol efflux
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br Experimental design materials and
2018-10-23
Experimental design, materials and methods Acknowledgments This work was financially supported by the Modern Agricultural Industry Technology System (CARS-37), the Key Project of Agricultural Fine Breeding of Shandong Province (2012LZ15), and the Support Program of Tai Mountain Scholar Talent
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Current voltage I V characterization was
2018-10-23
Current–voltage (I–V) characterization was conducted using a Keithley 2400 source measurement apparatus in a four-wire setup in ambient Nilotinib with an ORIEL solar simulator (class ABA) at AM 1.5G. A silicon reference cell (PV Measurements, Inc. 20mm×20mm) was used for the calibration of the illu
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