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We have explored the possibility of using the cardiac
2018-11-08

We have explored the possibility of using the cardiac MSCs of the human fetal heart for expansion of LDN193189 Hydrochloride with characteristics similar to those of mesenchymal progenitors that contribute to mammalian cardiogenesis. In this study cardiac MSCs were reproducibly recovered from the a
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To gain further insight into progenitor cells derived
2018-11-08

To gain further insight into progenitor xpo 1 derived from human skeletal muscle, we performed comprehensive cell-surface protein profiling of two progenitor populations, CD56+ myogenic progenitors and PDGFRα+ mesenchymal progenitors. This comprehensive analysis identified previously unrecognized m
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Flow cytometry analysis showed that independent
2018-11-07

Flow cytometry analysis showed that independent targeted clones expressed remarkably similar levels of the inserted reporter genes, highlighting the consistency of expression produced by this vector configuration (Figure 1C). This consistency also enabled us to conclude that all the selectable marke
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br Conclusions The results indicate that in general chances
2018-11-07

Conclusions The results indicate that, in general, chances in the Brazilian budgetary institutions have contributed to a better primary result of the federal government, particularly those changes captured by the indices that evaluate the budget categories and stages IC and IS and the sub-indices
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If cesarean delivery has a prolonged effect
2018-11-07

If cesarean delivery has a prolonged effect on the microbiota, this could contribute to the risk for metabolic diseases later in life. Herein, we explored whether the fecal microbiota differs between adults who reported that they were born by cesarean versus vaginal delivery. For comparison, in the
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The contemporary physicians have more knowledge about this c
2018-11-07

The contemporary physicians have more knowledge about this condition, and in the diagnosis and in therapeutic choices, given that the treatment should be individualized for each patient. The high costs of the treatments, the lack of therapeutic adherence as well as inadequate compliance of the patie
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br Materials Methods br Results br Discussion To
2018-11-07

Materials & Methods Results Discussion To test the role of the Mbnl family of proteins in skeletal muscle function we have developed and examined transgenic mouse strains that show single and combinatorial deficits in the three muscleblind proteins, Mbnl1, Mbnl2 and Mbnl3. In contrast with
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br Material and Methods br Results br Discussion
2018-11-07

Material and Methods Results Discussion In this study, we show significant differences in the infectivity and cellular response between two Asian and African ZIKV strains. Using a combination of cell and molecular biology approaches, we observed in two human neural cell types (NSCs and astr
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br Conclusions br Funding Sources This
2018-11-07

Conclusions Funding Sources This work is supported by the Wellcome Trust through a Strategic Award, reference 104036/Z/14/Z. GS:SFHS was funded by a grant from the Scottish Government Health Department, Chief Scientist Office, number CZD/16/6. The authors acknowledge with gratitude the financi
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br Acknowledgements The authors would
2018-11-07

Acknowledgements The authors would like to thank Patricia Lemnitzer, Yvonne Jansen, Janine Brauner, and Sebastian Cucuruz for excellent technical assistance. The graphical abstract was designed by Patrick Paulin ([email protected]). We thank Lars König for providing HepG2 cells. Introd
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Children with increased gut permeability had higher serum
2018-11-07

Children with increased gut permeability had higher serum concentrations of four odd-chain fatty acids. Less is known about odd-chain fatty acids compared with even-chain fatty acids, since they represent JNK inhibitor plasma concentrations in humans (Jenkins et al., 2015). The etiology of the incr
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Fig demonstrates the modal intensity of the proposed
2018-11-07

Fig. 2 demonstrates the modal intensity of the proposed PCF for both of elliptical and circular holes in core region in X-polarization and Y-polarization mode respectively. We have compiled two proposed PCF based sensor using FEM based commercial tool COMSOL Multiphysics version 4.2. Furthermore, fi
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Invivo Hx depletion in mouse
2018-11-07

Invivo, Hx depletion in mouse models of hemolytic disorders, β-thalassemic mice and phenylhydrazine (PHZ)-treated mice, was associated with heme accumulation and oxidative stress in the heart. Data show that in β-thalassemic mice, low Hx serum level, was associated to increased expression of heme- a
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Samples were biofunctionalized using plasma electrolytic oxi
2018-11-07

Samples were biofunctionalized using plasma electrolytic oxidation on a custom-made laboratory setup. Details regarding the experimental setup can be found in [1]. Plasma electrolytic oxidation is an electrochemical process, which drives uniform growth of the titanium oxide (TiO2) layer on the surfa
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The DA system undergoes significant reorganization over adol
2018-11-07

The DA system undergoes significant reorganization over adolescence, which is implicated in the pathophysiology of various disorders that appear during adolescence (see Nelson et al., 2005; Spear, 2000; Wahlstrom et al., 2010a). Across rodents, non-human primates, and humans, increases in dopamine s
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