• The contemporary physicians have more knowledge about this c

  2018-11-07

  

  The contemporary physicians have more knowledge about this condition, and in the diagnosis and in therapeutic choices, given that the treatment should be individualized for each patient. The high costs of the treatments, the lack of therapeutic adherence as well as inadequate compliance of the patie

• br Materials Methods br Results br Discussion To

  2018-11-07

  

  Materials & Methods Results Discussion To test the role of the Mbnl family of proteins in skeletal muscle function we have developed and examined transgenic mouse strains that show single and combinatorial deficits in the three muscleblind proteins, Mbnl1, Mbnl2 and Mbnl3. In contrast with

• br Material and Methods br Results br Discussion

  2018-11-07

  

  Material and Methods Results Discussion In this study, we show significant differences in the infectivity and cellular response between two Asian and African ZIKV strains. Using a combination of cell and molecular biology approaches, we observed in two human neural cell types (NSCs and astr

• br Conclusions br Funding Sources This

  2018-11-07

  

  Conclusions Funding Sources This work is supported by the Wellcome Trust through a Strategic Award, reference 104036/Z/14/Z. GS:SFHS was funded by a grant from the Scottish Government Health Department, Chief Scientist Office, number CZD/16/6. The authors acknowledge with gratitude the financi

• br Acknowledgements The authors would

  2018-11-07

  

  Acknowledgements The authors would like to thank Patricia Lemnitzer, Yvonne Jansen, Janine Brauner, and Sebastian Cucuruz for excellent technical assistance. The graphical abstract was designed by Patrick Paulin ([email protected]). We thank Lars König for providing HepG2 cells. Introd

• Children with increased gut permeability had higher serum

  2018-11-07

  

  Children with increased gut permeability had higher serum concentrations of four odd-chain fatty acids. Less is known about odd-chain fatty acids compared with even-chain fatty acids, since they represent JNK inhibitor plasma concentrations in humans (Jenkins et al., 2015). The etiology of the incr

• Fig demonstrates the modal intensity of the proposed

  2018-11-07

  

  Fig. 2 demonstrates the modal intensity of the proposed PCF for both of elliptical and circular holes in core region in X-polarization and Y-polarization mode respectively. We have compiled two proposed PCF based sensor using FEM based commercial tool COMSOL Multiphysics version 4.2. Furthermore, fi

• Invivo Hx depletion in mouse

  2018-11-07

  

  Invivo, Hx depletion in mouse models of hemolytic disorders, β-thalassemic mice and phenylhydrazine (PHZ)-treated mice, was associated with heme accumulation and oxidative stress in the heart. Data show that in β-thalassemic mice, low Hx serum level, was associated to increased expression of heme- a

• Samples were biofunctionalized using plasma electrolytic oxi

  2018-11-07

  

  Samples were biofunctionalized using plasma electrolytic oxidation on a custom-made laboratory setup. Details regarding the experimental setup can be found in [1]. Plasma electrolytic oxidation is an electrochemical process, which drives uniform growth of the titanium oxide (TiO2) layer on the surfa

• The DA system undergoes significant reorganization over adol

  2018-11-07

  

  The DA system undergoes significant reorganization over adolescence, which is implicated in the pathophysiology of various disorders that appear during adolescence (see Nelson et al., 2005; Spear, 2000; Wahlstrom et al., 2010a). Across rodents, non-human primates, and humans, increases in dopamine s

• Recent research additionally suggests a crucial

  2018-11-07

  

  Recent research additionally suggests a crucial role for the BG in filtering information into WM. Evidence for this Atractyloside Dipotassium Salt comes from several sources. Computational models of WM that model the BG as responsible for selectively updating information in WM reproduce core human

• We have previously reported developmental changes in reversa

  2018-11-07

  

  We have previously reported developmental changes in reversal learning in mice (Johnson and Wilbrecht, 2011) using a 4-choice, odor-based digging task (similar to the ASST but with 4 choices). We also established this task is dependent on the integrity of the dorsomedial frontal purchase PLX4720 (d

• Introduction The role of a surgical margin in surgical

  2018-11-06

  

  Introduction The role of a surgical margin in surgical oncology has always been discussed with regard to the tumor recurrence and survival rate in gastrointestinal cancer surgery. Previous reports have suggested that extensive operation with a wide resection margin and extensive muscarinic receptor

• Less reconstructive methods with infective and exposed

  2018-11-06

  

  Less reconstructive methods with infective and exposed sternal wounds have been reported because of the challenges of dead space obliteration, infection control, and unstable hemodynamics. According to the studies reviewed, four methods have been reported for wide and open sternal wound reconstructi

• Obesity in general is a predisposing

  2018-11-06

  

  Obesity in general is a predisposing factor of OA. There is a strong association between overweight and hip and knee OA. However, the association between overweight and ankle OA remains unclear. In Frey and Zamora\'s study regarding overweight and ankle OA, a total of 887 women and 535 men were incl

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