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Recently a reciprocal fusion between YPEL yippee
2019-04-16

Recently, a reciprocal fusion between YPEL5 (yippee-like 5) and PPP1CB (serine/threonine protein phosphatase-1 beta catalytic subunit) was described to be exclusively expressed in more than 90% of primary CLL samples [5] and not in control samples or samples from patients with other hematological ma
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To overcome these resistance mechanisms
2019-04-16

To overcome these resistance mechanisms in APL cells, a number of drugs have been tested. Tamibarotene is approximately 10 times more potent than ATRA as an in vitro inducer of differentiation, and is chemically more stable than ATRA [5]. Although the precise mechanism of the combination of tamibaro
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The study by Mijiti and colleagues also illustrates
2019-04-16

The study by Mijiti and colleagues also illustrates that, besides medical factors, social determinants of health—poverty, education, geography, customs, etc—also play an important role in tuberculosis control. Owing to the low socioeconomic status and poor social health environment, tuberculosis mai
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br Material and methods br
2019-04-16

Material and methods Results Discussion In our series, fracture progression was noted in 53% of the lesions and 5 patients presented with new fractures after RT. Previous studies reported on the rate of pathologic fractures after single or multifraction RT; however, they did not stratify be
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Along the same line there is no
2019-04-16

Along the same line, there is no information in the literature on the optimal RT schedule in such cases. Doses ranging from 40 to 45Gy should be adequate and we chose to give 2Gy daily. This schedule was based on clinical and radiological evolution of the patient. RT limits natural evolution of the
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br Case report A year old patient with pectus
2019-04-16

Case report A 38-year-old patient with pectus excavatum received a dual chamber ICD after resuscitated cardiac arrest due to ventricular fibrillation during myocardial infarction following vasculitis (Fig. 1, Panel A). He developed fever and chill after the ICD implantation, consistent with the g
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br Methods This prospective study was conducted at
2019-04-15

Methods This prospective study was conducted at the Zekai Tahir Burak Woman\'s Health, Research and Education Hospital, Ankara, Turkey between April 2009 and August 2009. The study was approved by the local Ethics Committee of the hospital, and an informed consent was signed by all patients befor
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Introduction Schwannoma is a benign
2019-04-15

Introduction Schwannoma is a benign tumor of neuroectodermal derivation that originates from Schwann nucleoside transporters which cover the peripheral nerves [3]. Approximately 25–40% of all schwannomas occur in the head and neck. These tumors most commonly arise in the soft tissues of the head
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Coincidente con esta perspectiva Tadeo
2019-04-15

Coincidente con esta perspectiva, Tadeo es un escritor que busca alejarse del vulgo y considera que la gran literatura no puede ser comprendida por todos. Su ensimismamiento lo conduce al desprecio por los otros y prostaglandin synthase un aislamiento extremo, donde al final ni siquiera es capaz de
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mct2 inhibitor br The Medical Education Partnership Initiati
2019-04-15

The Medical Education Partnership Initiative (MEPI) is an innovative and potentially transformative 5-year programme, established by the US Government in 2010, to increase the number of doctors to meet crucial human resource needs in sub-Saharan Africa. MEPI allows African institutions that mct2
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Introduction Leukaemias lymphomas and multiple myeloma can b
2019-04-15

Introduction Leukaemias, lymphomas and multiple myeloma can be the dreadful sequelae of viral infections. RNA oncogenic viruses, which are also known as retroviruses, were initially known to cause lymphoproliferative disorders only in animals, but have also been reported to demonstrate their transf
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Narcolepsy may be mono symptomatic only ES or oligo
2018-11-15

Narcolepsy may be mono-symptomatic (only ES) or oligo-symptomatic (ES and cataplexy). The degree of ES is variable and the attacks of cataplexy might involve several muscle groups being triggered by emotions [1,3]. The use of modafinil in the treatment of narcolepsy is a first option for the treatm
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br Introduction Narcolepsy is a
2018-11-15

Introduction Narcolepsy is a chronic disturbance that leaves patients incapacitated in most cases; it is characterized by an abnormal sleep pattern that may include excessive daytime sleepiness, sleep architecture alterations, and rapid eye movement (REM) sleep pathological manifestations, includ
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Each participant was equipped with two actigraphs
2018-11-15

Each participant was equipped with two actigraphs (MTI® model 7164 accelerometer, ActiGraph, Pensacola, FL); one was worn on the non-dominant wrist, and the other was affixed to the hip. The actigraphs were initialized prior to recording using the same computer that was used for PSG recording so tha
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Each participant was equipped with two actigraphs
2018-11-15

Each participant was equipped with two actigraphs (MTI® model 7164 accelerometer, ActiGraph, Pensacola, FL); one was worn on the non-dominant wrist, and the other was affixed to the hip. The actigraphs were initialized prior to recording using the same computer that was used for PSG recording so tha
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